جون سلستن
جون سلستن John E. Sulston | |
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وُلِدَ | John Edward Sulston 27 مارس 1942[1] |
توفي | 6 مارس 2018 | (aged 75)
الجنسية | English |
الجنسية | Britain |
التعليم | Merchant Taylors' School, Northwood |
المدرسة الأم | University of Cambridge (BA, PhD) |
اللقب | Genome sequencing of Caenorhabditis elegans and humans[2][3][4][5] Sulston score[6] استموات |
الزوج |
Daphne Edith Bate (m. 1966) |
الأنجال | 1 son, 1 daughter[1] |
الجوائز |
|
السيرة العلمية | |
المجالات | |
الهيئات | |
أطروحة | Aspects of oligoribonucleotide synthesis (1966) |
المشرف على الدكتوراه | Colin Reese[10][11] |
أثـَّر عليه | |
الموقع الإلكتروني | sanger |
جون إدوارد سلستن John E. Sulston، (و. 27 مارس 1942[13][14])، هو عالم أحياء بريطاني. حصل على جائزة نوبل في الطب سنة 2002 for his work on the cell lineage and genome of the worm Caenorhabditis elegans in 2002 with his colleagues سيدني برنر و Robert Horvitz. He was a leader in human genome research and Chair of the Institute for Science, Ethics and Innovation at the University of Manchester.[15][16][17] Sulston was in favour of science in the public interest, such as free public access of scientific information and against the patenting of genes and the privatisation of genetic technologies.[18]
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النشأة
Sulston was born in Fulmer, Buckinghamshire, England[19] to Arthur Edward Aubrey Sulston and Josephine Muriel Frearson, née Blocksidge.[1][20] His father was an Anglican priest and administrator of the Society for the Propagation of the Gospel. His mother quit her job as an English teacher at Watford Grammar School, to care for him and his sister Madeleine.[21] and home-tutored them until he was five. At age five he entered the local preparatory school, York House School, where he soon developed an aversion to games. He developed an early interest in science, having fun with dissecting animals and sectioning plants to observe their structure and function.[11] Sulston won a scholarship to Merchant Taylors' School, Northwood[1] and then to Pembroke College, Cambridge graduating in 1963 with a Bachelor of Arts[1] degree in Natural Sciences (Chemistry). He joined the Department of Chemistry, University of Cambridge, after being interviewed by Alexander Todd[11][22] and was awarded his PhD in 1966 for research in nucleotide chemistry.[10]
السيرة
لعب سلستن دوراً مركزياً في مشروعي تسلسل جينوم الدودة Caenorhabditis elegans [3] والجينوم البشري[23]. He had argued successfully for the sequencing of C. elegans to show that large-scale genome sequencing projects were feasible. As sequencing of the worm genome proceeded, the project to sequence the human genome began. At this point he was made director of the newly established Sanger Centre (named after فرد سانگر and now the وقف ولكم معهد سانگر)، الكائن في كمبردجشاير، إنگلترة.
وقد قام سلستن بدفع الكفالة المطلوبة من جوليان أسانج، حسب مارك ستيفنز، محامي جوليان. [1].
انظر أيضا
وصلات خارجية
سيرة ذاتية
- PLoS Biology: All for All
- John Sulston biography from the Wellcome Trust
- John Sulston: Nobel Prize in Physiology or Medicine 2002
- Portraits of John Sulston from the National Portrait Gallery (United Kingdom)
- John Sulston profile from Channel4
- John Sulston profile from BBC4
- Freeview Video of Fredrick Sanger in conversation with John Sulston by the Vega Science Trust
- John Sulston profile from the Medical Research Council lab for Molecular Biology
- John Sulston FRS interview from the Royal Society
- Sir John Sulston FRS - Worm genomics
- John Sulston interviewed by Alan Macfarlane 16th September 2008 (film)
المنشورات
أخبار ومعلومات
- Sir John Sulston awarded the 2002 Nobel Prize (press release from the Sanger Centre)
- The public servant: John Sulston
- British Scientists share 2002 Nobel Prize
- John Sulston: One man and his worm from The Guardian
مناصب منظمات غير ربحية | ||
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سبقه – |
مدير معهد سانگر 1993–2000 |
تبعه ألان برادلي |
قالب:FRS 1986 قالب:Wellcome Trust
- ^ أ ب ت ث ج ح قالب:Who's Who (يتطلب اشتراك)
- ^ Wilson, R.; Ainscough, R.; Anderson, K.; Baynes, C.; Berks, M.; Bonfield, J.; Burton, J.; Connell, M.; Copsey, T.; Cooper, J.; Coulson, A.; Craxton, M.; Dear, S.; Du, Z.; Durbin, R.; Favello, A.; Fraser, A.; Fulton, L.; Gardner, A.; Green, P.; Hawkins, T.; Hillier, L.; Jier, M.; Johnston, L.; Jones, M.; Kershaw, J.; Kirsten, J.; Laisster, N.; Latreille, P.; Lightning, J. (1994). "2.2 Mb of contiguous nucleotide sequence from chromosome III of C. Elegans". Nature. 368 (6466): 32–38. Bibcode:1994Natur.368...32W. doi:10.1038/368032a0. PMID 7906398. S2CID 21450455.
- ^ أ ب Sulston, J.; Brenner, S. (1974). "The DNA of Caenorhabditis elegans". Genetics. 77 (1): 95–104. doi:10.1093/genetics/77.1.95. PMC 1213121. PMID 4858229.
- ^ Sulston, J. E.; Schierenberg, E.; White, J. G.; Thomson, J. N. (1983). "The embryonic cell lineage of the nematode Caenorhabditis elegans". Developmental Biology. 100 (1): 64–119. doi:10.1016/0012-1606(83)90201-4. PMID 6684600.
- ^ Sulston, J. E.; Horvitz, H. R. (1977). "Post-embryonic cell lineages of the nematode, Caenorhabditis elegans". Developmental Biology. 56 (1): 110–156. doi:10.1016/0012-1606(77)90158-0. PMID 838129.
- ^ Sulston, J.; Mallett, F.; Staden, R.; Durbin, R.; Horsnell, T.; Coulson, A. (1988). "Software for genome mapping by fingerprinting techniques". Computer Applications in the Biosciences. 4 (1): 125–132. doi:10.1093/bioinformatics/4.1.125. PMID 2838135.
- ^ خطأ استشهاد: وسم
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- ^ خطأ استشهاد: وسم
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- ^ خطأ استشهاد: وسم
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- ^ أ ب Sulston, John Edward (1966). Aspects of oligoribonucleotide synthesis. repository.cam.ac.uk (PhD thesis). University of Cambridge. doi:10.17863/CAM.16307. قالب:EThOS. قالب:Free access
- ^ أ ب ت ث John E. Sulston on Nobelprize.org , accessed 11 أكتوبر 2020
- ^ Dunitz, J. D.; Joyce, G. F. (2013). "Leslie Eleazer Orgel. 12 January 1927 -- 27 October 2007". Biographical Memoirs of Fellows of the Royal Society. 59: 277–289. doi:10.1098/rsbm.2013.0002. S2CID 72244996.
- ^ Kolata, Gina (15 March 2018). "John E. Sulston, 75, Dies; Found Clues to Genes in a Worm". The New York Times.
- ^ Waterston, Robert H.; Ferry, Georgina (2019). "Sir John Edward Sulston CH. 27 March 1942 – 6 March 2018". Biographical Memoirs of Fellows of the Royal Society. 67: 421–447. doi:10.1098/rsbm.2019.0014. S2CID 186212646.
- ^ "Professor Sir John Sulston - personal details". The University of Manchester. Archived from the original on 11 October 2009. Retrieved 6 November 2014.
- ^ Gitschier, Jane (2006). "Knight in Common Armor: An Interview with Sir John Sulston". PLOS Genetics. 2 (12): e225. doi:10.1371/journal.pgen.0020225. PMC 1756915. PMID 17196043.
{{cite journal}}
: CS1 maint: unflagged free DOI (link) - ^ Sulston, J. (2002). "A conversation with John Sulston". The Yale Journal of Biology and Medicine. 75 (5–6): 299–306. PMC 2588810. PMID 14580111.
- ^ Ivan Oransky, Adam Marcus John Sulston. obituary 7 April 2018, The Lancet
- ^ Ferry, Georgina (11 March 2018). "Sir John Sulston obituary". The Guardian.
- ^ "John E. Sulston". NNDB. Soylent Communications. Retrieved 21 April 2014.
- ^ "John Sulston Biography Nobel Prize in Medicine". American Academy of Achievement. Archived from the original on 23 April 2014. Retrieved 21 April 2014.
- ^ Brown, D. M.; Kornberg, H. (2000). "Alexander Robertus Todd, O.M., Baron Todd of Trumpington. 2 October 1907 -- 10 January 1997: Elected F.R.S. 1942". Biographical Memoirs of Fellows of the Royal Society. 46: 515–532. doi:10.1098/rsbm.1999.0099. S2CID 73076704.
- ^ PMID 11237011 (PubMed)
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- Short description is different from Wikidata
- مواليد 1942
- أشخاص أحياء
- حائزو جائزة نوبل بريطانيون
- زملاء الجمعية الملكية
- إنسانيون بريطانيون
- ملحدون إنگليز
- مسيحيون سابقون إنگليز
- أعضاء المنظمة الأوروبية لعلم الأحياء الجزيئي
- خريجو جامعة كمبردج
- أكاديميو جامعة كمبردج
- أكاديميو جامعة مانشستر
- الحاصلون على لقب فارس
- حائزو جائزة نوبل في الطب
- Wellcome Trust
- علماء مشروع الجينوم البشري
- Caenorhabditis elegans
- أعضاء مرتبة رفاق الشرف
- صفحات تحتوي روابط لمحتوى للمشتركين فقط
- Nobelprize template using Wikidata property P8024
- CS1 maint: unflagged free DOI
- Pages with incomplete PMID references