قالب:PBB/51738

قبل برو الببتيد جريلين/أوبيستاتين
البنى المتاحة
1P7X
المحددات
الرمزs	GHRL; MTLRP
المحددات الخارجية	OMIM: 605353 MGI: 1930008 هومولوجين: 9487 GeneCards: GHRL Gene
طبيعة الجين الوظيفة الجزيئية • G-protein coupled receptor binding • growth hormone-releasing hormone activity • protein tyrosine kinase activator activity • ghrelin receptor binding المكون الخلوي • extracellular region • extracellular space • endoplasmic reticulum lumen • axon • secretory granule lumen العملية الحيوية • activation of MAPK activity • gastric acid secretion • negative regulation of endothelial cell proliferation • glucose metabolic process • G-protein coupled receptor signaling pathway • elevation of cytosolic calcium ion concentration • actin polymerization or depolymerization • adult feeding behavior • response to hormone stimulus • hormone-mediated signaling pathway • dendrite development • negative regulation of angiogenesis • growth hormone secretion • positive regulation of insulin secretion • positive regulation of appetite • negative regulation of interleukin-1 beta production • negative regulation of locomotion • positive regulation of multicellular organism growth • regulation of cell proliferation • negative regulation of circadian sleep/wake cycle, REM sleep • negative regulation of tumor necrosis factor biosynthetic process • negative regulation of apoptotic process • cortisol secretion • response to estrogen stimulus • cellular protein metabolic process • negative regulation of interleukin-6 biosynthetic process • positive regulation of circadian sleep/wake cycle, non-REM sleep • negative regulation of insulin secretion • decidualization • negative regulation of inflammatory response • cartilage development • positive regulation of corticotropin secretion • positive regulation of cortisol secretion • positive regulation of synapse assembly • regulation of excitatory postsynaptic membrane potential • positive regulation of growth hormone secretion • positive regulation of growth hormone receptor signaling pathway • positive regulation of protein tyrosine kinase activity
الكروموسومات المتناددة Orthologs
النوع	بشري	فأري
Entrez	51738	58991
Ensembl	ENSG00000157017	ENSMUSG00000064177
UniProt	Q9UBU3	Q9EQX0
RefSeq (mRNA)	NM_001134941	NM_021488
RefSeq (protein)	NP_001128413	NP_067463
الموقع (UCSC)	Chr 3: 10.33 - 10.33 Mb	Chr 6: 113.72 - 113.72 Mb
بحث PubMed	[1]	[2]