قشرة الكظر
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Details | |
Identifiers | |
اللاتينية | cortex glandulae suprarenalis |
MeSH | D000302 |
TA98 | A13.2.03.005%20Entity%20TA98%20EN.htm A11.5.00.007، A13.2.03.005 |
TA2 | 3881 |
FMA | 15632 |
المصطلحات التشريحية |
Situated along the perimeter of the adrenal gland, the adrenal cortex mediates the stress response through the production of mineralocorticoids and glucocorticoids, including aldosterone and cortisol respectively. It is also a secondary site of androgen synthesis.
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الطبقات
القشرة يمكن تقسيمها إلى ثلاث طبقات مميزة من الأنسجة بناء على تكوينهم.
الطبقة | الاسم | الناتج الرئيسي |
Most superficial cortical layer | zona glomerulosa | mineralocorticoids (eg, aldosterone) |
Middle cortical layer | zona fasciculata | glucocorticoids (eg, cortisol) |
Deepest cortical layer | zona reticularis | weak androgens (eg, dehydroepiandrosterone) |
خطوات تخليق الهرمون
- All adrenocortical hormones are synthesised from cholesterol.
Mnemonics
طبقات القشرة يمكن تذكـُّرهم عن طريق can be remembered with the mnemonic GFR: G - glomerulosa, F - fasciculata, R - reticularis.
Another mnemonic that is used is Go Find Rex, Make Good Sex: G - glomerulosa, F - fasciculata, R - reticularis, M - mineralcorticoids, G - glucocorticoids, S - sex hormones. (This mnemonic simplifies the relationship between the locations of production of glucocorticoids and sex hormones.)
Another mnemonic is "Salt, Sugar, Sex: The deeper you go, the sweeter it gets." As one moves layers into the adrenal cortex, compounds that control salt (mineralcorticoids), sugar (glucocorticoids), and sex (weak androgens) are produced.
پاثولوجيا
- Adrenal insufficiency (e.g. due to Addison's disease)
- Cushing's syndrome
- Congenital adrenal hyperplasia
- Conn's syndrome
انظر أيضاً
وصلات داخلية
- SUNY Labs 40:04-0203 - "Posterior Abdominal Wall: Blood Supply to the Suprarenal Glands"
- Mnemonic at medicalmnemonics.com 180 2201 412
- Histology at BU 14502loa
- Anatomy Atlases - Microscopic Anatomy, plate 15.292 - "Adrenal Gland"
- Adrenal Cortex Medical Notes on rahulgladwin.com